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Targeted sequencing of pathogenic microorganisms (tNGS)

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The ultra-multiplex PCR technology independently developed by Bingyuan Shengkang has been utilized by several domestic and international institutions for research or the development of clinical diagnostic products. It can complete over 10,000 multiplex PCR reactions in a single tube within a few hours, offering exceptional information amplification capabilities. Through the integration of an automated platform, it has ultimately developed powerful diagnostic products with a high signal-to-noise ratio for pathogen auxiliary diagnosis. 

Targeted next-generation sequencing (tNGS) testing combines ultra-multiplex PCR with high-throughput sequencing technology, allowing for the simultaneous detection of hundreds of common pathogenic microorganisms and various resistance genes. This approach efficiently eliminates interference from human nucleic acids and background microorganisms, enabling rapid assessment of pathogen infections and resistance. It improves sensitivity while achieving dual optimization of cost and performance, making diagnostics more accessible for patients and effectively supporting precise diagnosis and treatment.



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Suspected Infection 

Highly suspected infectious disease, but the etiological diagnosis is unclear and conventional anti-infection treatment is ineffective. Identification of the pathogen is needed to achieve precise treatment.

Critical Illness

Presentation of acute critical illness, where infection is not ruled out, or there is a consideration of secondary or complicated life-threatening severe infections.

Secondary Infection

Suspected secondary infection in immunocompromised patients, where conventional etiological examinations fail to identify the pathogen and/or empirical anti-infection treatments are ineffective.

Chronic Infection

Emphasizing chronic infection, or chronic disease not ruling out infection, when clinical manifestations are difficult to differentiate, severe conditions or ineffective anti-infection treatment.

Suspected Antibiotic-Resistant Infection

Unsatisfactory clinical treatment results necessitate clarification of whether the infecting strain is resistant, leading to adjustments in the treatment plan.

Fever of Unknown Origin

Fever or fever syndrome with an unclear cause, considering infection or not ruling out infection, but normative empirical anti-infection treatment is ineffective.

Local Infection

Suspected local infection with unclear etiological diagnosis; if not addressed in a timely manner, the consequences could be severe.



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